Question: Hi David, I have a case I am working on for a long time with this 5yo girl and would need your advice on how to help. I m sending details in the following message. ADAMTS13 SummaryGene location The ADAMTS13 gene is located on:* Chromosome 9* region: 9q34.2ADAMTS13 \in 9q34.2⸻Child’s mutations (patient 2023#105)The child has:two different ADAMTS13 mutations(one on each chromosome 9 = “in trans”)⸻Paternal mutationInherited from the father:* Exon: 5* Nucleotide change: c.536C>T* Protein change: p.Thr179Ile* Classification: * VUS / likely deleteriousc.536C>T \rightarrow p.Thr179Ile⸻Maternal mutationInherited from the mother:* Exon: 26* Nucleotide change: c.3655C>T* Protein change: p.Arg1219Trp* Classification: * pathogenicc.3655C>T \rightarrow p.Arg1219Trp⸻Meaning of “in trans”The mutations are located on:* different copies of chromosome 9,* one inherited from the father,* one inherited from the mother.Therefore, the child has no completely normal ADAMTS13 copy.⸻ResultThis causes:severe ADAMTS13 deficiency (<1%)consistent with:congenital/hereditary TTP (cTTP/hTTP).
Answer:
Thank you for the detailed summary. In this case, I would be very careful: this is not primarily a “detox” or infection case; it is a severe congenital ADAMTS13 enzyme-deficiency condition, consistent with hereditary/congenital TTP. Biomagnetism may be used only as supportive regulation, never as a substitute for pediatric hematology management.
The child appears to have compound heterozygous ADAMTS13 mutations in trans, with ADAMTS13 activity reported as <1%. That fits the logic of congenital TTP / hereditary TTP, where the body cannot adequately cleave ultra-large von Willebrand factor multimers. When ADAMTS13 is profoundly deficient, platelets can form small-vessel microthrombi, causing thrombocytopenia, hemolysis, and possible neurologic, renal, cardiac, or abdominal complications. cTTP is classically linked to biallelic ADAMTS13 mutations and severe ADAMTS13 activity, often below 10%.
This child needs to remain under a pediatric hematologist or a thrombotic microangiopathy/TTP specialist. The medical center should have a clear plan for:
CBC with platelets, hemoglobin, LDH, bilirubin, creatinine, urinalysis, peripheral smear, ADAMTS13 activity, and inhibitor/neutralizing antibody monitoring.
Modern treatment is based on ADAMTS13 replacement. The FDA lists recombinant ADAMTS13, ADZYNMA, as prophylactic or on-demand enzyme replacement therapy for adult and pediatric congenital TTP patients. Current ISTH updates also support ADAMTS13 replacement in cTTP, with recombinant ADAMTS13 favored where accessible. Important caution: in November 2025, the FDA reported postmarketing cases of neutralizing antibodies to ADAMTS13, including one pediatric death, in patients treated with ADZYNMA. This does not mean the treatment should be avoided automatically, but it does mean the hematologist should monitor carefully for inhibitors/antibodies and loss of response.
From Biomagnetism, I would not try to “correct the gene” or promise that the therapy will prevent TTP crises. That would not be scientifically responsible.
The realistic objective would be: support autonomic balance, reduce physiological stress load, support sleep, digestion, liver-kidney regulation, immune stability, and general resilience.
In practical terms, I would work gently and consistently. In a 5-year-old, I would avoid very heavy protocols, excessive “detox” language, or provoking strong recovery reactions. If the child becomes pale, weak, jaundiced, bruised, febrile, confused, sleepy, or neurologic, that is not a healing crisis; that is a medical warning sign.
She needs a full scan every session. Do not rely only on preset protocols.
As complementary support, I would consider:
Protocol 83. Hematologic
Not to “treat TTP,” but to observe how the body is expressing the hematologic imbalance.
Protocol 84. immunological
Useful because infections can trigger TTP episodes in hereditary ADAMTS13 deficiency. Episodes may remain silent until triggered by factors such as infection, surgery, pregnancy later in life, or other physiologic stressors.
Protocol 65. Basic Detox
Very gently, because hemolysis and microangiopathy can involve kidney stress.
Protocol 60. Relaxation
Especially if there is anxiety, poor sleep, irritability, trauma from illness, or repeated hospital experiences.
Protocol 32. Microbiota
Only as general systemic support, not as the central treatment.
Protocol 11. Cerebral Blood Supply
Only when stable. If there are headaches, confusion, weakness, seizures, speech difficulty, visual changes, or abnormal sleepiness, that is emergency care first.
For home use, I would keep it simple and gentle. Do not use too many magnets in a small child.
Possible pairs:
Cervical Plexus – Cervical Plexus
Kidney – Kidney
Liver – Liver
Adrenal – Adrenal
Temporal – Temporal
Colon – Liver
Hip – Hip, if you want immune support
Spleen – Spleen
For a 5-year-old, I would start with:
20 minutes per session
If well tolerated after several sessions:
25–30 minutes
I would not begin with 60-minute home applications in this case.
Professional sessions:
1 time per week, or every 10–15 days if the child is medically stable.
Home pairs:
2 times per week at first.
If there is fatigue, irritability, poor sleep, bruising, pallor, fever, or any unusual symptom, reduce or stop home application and prioritize medical evaluation.
As supportive care:
3 months initially, then reassess.
If stable and well tolerated:
3–6 months as a gentle regulation plan.
But the medical condition itself is lifelong; Biomagnetism does not replace long-term hematology follow-up or ADAMTS13 replacement planning.
Keep hydration very good, especially during fever, vomiting, diarrhea, hot weather, or physical exertion.
Have a written emergency plan from the hematologist.
Before dental procedures, surgery, vaccines, or significant infections, the family should contact hematology. Vaccines should not be stopped casually, but they may need timing and monitoring in coordination with the specialist.
Avoid high-impact trauma activities if platelet counts are low.
Avoid aspirin, NSAIDs, supplements with anticoagulant effect, or “blood-thinning” products unless the hematologist approves.
Emergency evaluation is needed if there is:
new bruising, petechiae or purple spots
nosebleeds or gum bleeding
dark urine, jaundice, marked pallor
severe fatigue or sudden weakness
headache, confusion, seizures, sleepiness, vision changes
abdominal pain, vomiting, dehydration
chest pain, shortness of breath
fever or infection with worsening general condition
reduced urination or swelling
The mature clinical way to understand this case is: Biomagnetism may support regulation, but the central problem is severe ADAMTS13 deficiency. So the priority is hematology, enzyme replacement strategy, crisis prevention, and careful monitoring. Your role with Biomagnetism should be gentle, complementary, and very observant, never aggressive, never replacing medical treatment.
Question: What protocol would you recommend for Hammer toe on a 12 yr old boy who is growing very fast?
Answer:
For a 12-year-old with hammer toe who is growing very fast, I would not focus on “growth hormone” protocols. I would approach it as a mechanical–tendon–postural problem, using Biomagnetism as support for inflammation, pain, circulation, neuromuscular balance, and adaptation during growth.
Medically, he should also be evaluated by a pediatric orthopedist or podiatrist, especially to determine whether the toe is still flexible or already fixed.
Hammer toe usually means that one or more toes are bending abnormally because of tendon imbalance, muscle tension, shoe pressure, foot mechanics, or sometimes congenital/familial factors. In children, related deformities such as curly toes are often associated with flexion and deviation of the toe, commonly affecting the third and fourth toes.
The key clinical question is:
Can the toe still be straightened manually?
If it is flexible, conservative care may help more: footwear with enough toe space, stretching, exercises, taping, separators, orthotics, and physical therapy. AAOS mentions footwear changes and specific exercises as conservative measures for hammer toe, while other orthopedic sources describe treatment according to discomfort, rigidity, and function.
If it is already rigid, painful, causing calluses, or affecting gait, Biomagnetism can support symptoms, but it should not be presented as something that will mechanically reverse a fixed deformity.
Suggested protocols
I would suggest working in this order:
Full Biomagnetic Scan
This is important. Do not only treat the toe. In a fast-growing child, we need to review the whole system: spine, pelvis, hips, knees, ankles, feet, nervous system, inflammatory load, digestion, and endocrine adaptation.
Musculoskeletal / Orthopedic approach
Use the protocols 88, 92, 93 & 94 that covers joints, tendons, muscle tension, local pain, and postural compensation.
Pain and inflammation support
Use Protocol 84. Immunological and local pain approach such as joint – joint.
Circulation in legs and feet
Use Protocol 14. Leg Circulation because foot deformities can create compensatory tension in calves, ankles, plantar fascia, knees, and hips, I would include leg circulation support when indicated.
Relaxation / parasympathetic support
Use Protocol 60. Relaxation, not because the cause is “emotional,” but because muscle tone, pain perception, and tissue recovery are influenced by nervous system regulation.
Pairs suggested for home application
For home support, I would keep it simple:
Toe – Toe
Direct local work over the affected toe or toes, with double polarity.
Foot – Foot
For general support of the foot structure.
Ankle – Ankle
Useful if there is altered gait or tension around the ankle.
Gastrocnemius – Gastrocnemius
For calf tension, especially if the child walks with altered mechanics.
Knee – Knee
Only if there is compensation, pain, or altered alignment.
Hip – Hip
Important when growth is fast, because pelvic and hip mechanics influence the lower limb chain.
Adrenal – Adrenal
As support for inflammation, stress response, and adaptation.
Kidney – Kidney
As general detox and regulation support.
Cervical Plexus – Cervical Plexus
For parasympathetic relaxation.
Temporal – Temporal
If there is discomfort, anxiety, sleep disturbance, or nervous system irritability.
Time of application
For a 12-year-old, I would use moderate sessions:
30–40 minutes per session
3 times per week
Minimum 2–3 months, then reassess.
If there is pain after sports or walking, the local toe/foot/ankle pairs can be used as needed, but without overloading him.
What should be done medically
I would recommend:
A pediatric orthopedic or podiatry evaluation.
Assessment of whether the deformity is flexible or rigid.
Review of shoes: wide toe box, no compression.
Possible toe spacers, taping, orthotics, or physical therapy.
Stretching and strengthening exercises for toes, plantar fascia, calves, and foot intrinsic muscles.
Conservative measures such as appropriate footwear, orthotic support, taping, and exercises are commonly used before considering more invasive options.
General recommendations
Avoid tight shoes, narrow toe boxes, and shoes that force the toes forward.
Observe if the child walks on the outside or inside of the foot.
Check if there is calf tightness, flat feet, high arches, or knee/hip compensation.
Encourage stretching after activity, especially calves and plantar fascia.
Do not force the toe aggressively into position.
Warning signs
Refer promptly if there is increasing pain, numbness, wounds, calluses that worsen, limping, difficulty walking, rapid progression, loss of flexibility, or if the toe is already fixed and cannot be straightened manually.
The best way to understand this case is: Biomagnetism can support pain, inflammation, circulation, relaxation, and adaptation during growth, but the mechanical correction depends on whether the toe is flexible, the footwear, the tendons, and the orthopedic management. For this child, the priority is a full scan plus a conservative orthopedic strategy, not a hormone-growth protocol.
Question: Person with spinal stenosis - walking for more than 10 min causes the legs to give out. Sitting for a brief period of time brings relief and they can walk again. This person was a hiker and overall health is very good. This is becoming life changing for him. Are there any protocols that might help either reverse it or manage symptoms? Thank you so much. You are such a generous teacher.
Answer:
Thank you for your kind words. Clinically, this sounds very consistent with neurogenic claudication from lumbar spinal stenosis: walking or standing narrows the available space around the lumbar nerves, while sitting or bending forward often brings relief. Biomagnetism may help manage pain, inflammation, muscle tension, stress response, and functional tolerance, but I would not promise that it can “reverse” a structural stenosis.
In lumbar spinal stenosis, the spinal canal or nerve openings become narrowed. When the person walks upright, the lumbar spine tends to extend slightly, which can increase pressure on the nerve roots. When the person sits, leans forward, or rests briefly, the canal often opens a little and symptoms improve. This pattern is typical of neurogenic claudication.
So, from a teaching perspective, the goal is not simply “treat the legs.” The problem is usually lumbar nerve compression with secondary leg weakness, pain, heaviness, or numbness.
Medically, this person should be evaluated by a spine specialist, neurologist, orthopedist, or neurosurgeon, especially because the symptoms are already life-changing. Conservative treatment commonly includes physical therapy, core and hip work, flexion-biased exercises, medication when appropriate, and sometimes epidural injections. Surgery may be considered when symptoms are progressive, disabling, or not responding to conservative care.
With Biomagnetism, the evidence for static magnets in pain is still limited and not conclusive, so the most honest position is to use it as a complementary support, not as a substitute for imaging, medical follow-up, or decompressive treatment when that is needed.
I would work in layers:
1. Full Biomagnetic Scan
A complete rastreo is essential. In this case I would especially review lumbar spine, sacrum, hips, sciatic nerve pathway, gastrocnemius, vascular circulation in legs, inflammatory terrain, kidney/adrenal axis, liver/intestine, and nervous system regulation.
2. Protocol 94. Lumbar / 62. Sciatic Nerve / 14. Leg Circulation
3. Protocol 84. Immunological / 60. Relaxation
The logic here is not that these pairs “open the canal,” but that they may help the body tolerate pain, inflammation, muscular overload, medication burden, stress, and recovery demands.
4. Nervous System Regulation
This can be useful when pain has created fear of movement, sympathetic activation, poor sleep, or chronic guarding.
5. Leg Circulation / Walking Tolerance Support
This does not replace vascular evaluation, but it is clinically reasonable to support the lower extremities, especially when the patient describes heaviness or weakness.
A practical home routine could be:
Main routine, 3 times per week
If there is anxiety, poor sleep, or frustration
If there is clear leg heaviness
Apply the spinal/back magnets with the patient lying face up, placing the magnets on the bed first and then resting the back over them, so they do not need to lie face down.
A reasonable plan:
If there is no functional improvement after 2–3 months, or if symptoms are worsening, the medical plan needs to be escalated.
He should ideally have:
Walking aids such as trekking poles, a cane, or a walker can sometimes help because they allow slight forward flexion, which may reduce nerve pressure while walking.
He should avoid forcing long upright walks through weakness. Better options are often:
Also, magnets should be used cautiously or avoided near implanted medical devices such as pacemakers, defibrillators, or insulin pumps.
Seek urgent medical care if there is:
These signs can suggest serious nerve compression such as cauda equina syndrome.
The mature way to see this case is: Biomagnetism may help the terrain and symptoms, but spinal stenosis is often a mechanical compression problem. We can support inflammation, pain modulation, circulation, muscle tension, and nervous system balance, but we should not delay proper spine evaluation when walking capacity is clearly deteriorating.